On New Year's Eve, 1866, Gregor Mendel wrote to the prominent Swiss botanist Carl Nägeli to tell him about his now classic experiments with Pisum peas. In the margins of the letter, Nägeli scribbled a note: "only empirical and not rational." Two months later, Nägeli wrote back to Mendel, stating, "It seems to me that the experiments with Pisum, far from being finished, are only a beginning."













